Anion Requirements for Gastric Acid Secretion

Anion Requirements for Gastric Acid Secretion

The rate of hydrochloric acid production by isolated, bullfrog gastric mucosae depends critically on the supply of chloride ion to the serosal surface. Secretion of acid is negligible if chloride is completely replaced by glucuronate and gluconate ion. The experimental evidence indicates that the rate of acid secretion may be regarded as a reaction velocity, depending on chloride concentration ...

Gastric acid secretion.

PURPOSE OF REVIEW The present review summarizes the past year's literature, both clinical and basic science, regarding neuroendocrine and intracellular regulation of gastric acid secretion and proper use of antisecretory medications. RECENT FINDINGS Gastric acid kills microorganisms, modulates the gut microbiome, assists in digestion of protein, and facilitates absorption of iron, calcium, an...

Gastric Anion Exchange: Its Relation to the Immediate Mechanism of Hydrochloric Acid Secretion.

Maximal Gastric Acid Secretion in the Dog

As bstract. The reason for increased maximal acid secretory capacity in some patients with duodenal ulcer is uncertain. We postulated that chronically increased cephalic-vagal stimulation may be a cause of increased maximal acid output. To study this, we prepared six male, mongrel dogs with a vagally innervated gastric fistula, a vagally denervated fundic (Heidenhain) pouch, and a cervical esop...

Gastric acid secretion in chronic renal failure.

Contrary to the small amount of published evidence, but in accordance with clinical impression, we have found an increased incidence of peptic ulceration in people with chronic renal failure. Hyperacidic secretion in response to a standard pentagastrin test occurs in patients established on long-term dialysis treatment. The traditional liability of azotaemic patients to peptic ulceration seems ...